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Increasing access to safe and effective treatment of incomplete abortion in a primary health care setting at district level in Uganda.

The aim of this project is to increase access to safe post-abortion care (PAC) and decrease maternal mortality and morbidity from unsafe abortions in Uganda. To date, there is no established medical regimen for 2nd trimester PAC, instead unsafe methods (sharp curettage) are used. Our previous study in Uganda confirm the efficacy of medical management by midwives in 1st trimester PAC. We now aim to study efficacy and safety of medical vs. surgical treatment for 2nd trimester PAC in a randomised controlled trial. 1030 women, seeking care for incomplete 2nd trimester abortion at six health facilities in central Uganda, will be included. The use of sharp curettage will be monitored and evaluated during implementation. Primary outcome is the efficacy of treatment to expel the retained tissue without any additional surgical treatment. Secondary outcomes include safety, acceptability and contraceptive uptake. A study coordinating centre will be established in Kampala. Close collaboration between partner-researchers will facilitate study conduct (2016-2018). Preparations and training will occur during 2016, followed by recruitment during 2016-17 and data cleaning and analyses in 2018. Throughout the study period, in-service training of medical management in PAC will be held, workshops and policy-dialogues with stakeholders will be held to tailor-make service guidelines and to lobby for inclusion of medical management in policy. Two dissemination seminars will be held in 2016 and 2018

Project ID

SE-0-SE-29-2015-05904-285-12182

Activity status

2 - Implementation

Aid type

D02 - Other technical assistance

% to Uganda

100.00

Organisations

Funding

Sweden

Extending

The Swedish Research Council

Implementing

Karolinska Institutet

CRS code	%
Medical research (12182)	100.0